Evaluation of the response to cardiac resynchronization therapy in a group of patients attending a heart failure program

Evaluation of the response to cardiac resynchronization therapy in a group of patients attending a heart failure program

Drag. Clara Saldarriaga
Catalina Gallego Muñoz, Clara Inés Saldarriaga, Eliana Mabel Arenas Canas, Carolina Delgado Gómez and Carolina González Berrío
Colombian Journal of Cardiology
Publication date: 07/2017

Summary:

Introduction: cardiac resynchronization therapy is one of the treatment strategies
current for patients with heart failure and depressed systolic function, which has been shown to produce significant relief in symptoms, as well as improvement in ventricular function
left and long-term survival.
objective: assess response to cardiac resynchronization therapy after six months
of follow up.
Methodology: retrospective cohort analytical observational study, with nested analysis of
cases and controls, in which patients older than 18 years ˜ belonging to a
heart failure clinic and who were carriers of a cardiac resynchronization device.
Univariate analysis of the clinical and echocardiographic characteristics was performed and subsequently
a bivariate analysis of variables related to response to therapy.
Results: they included 92 patients with a history of heart failure and indication for therapy of
resynchronization; he 32,6% of patients had ischemic heart disease and 67,4% non ischemic,
with an average ejection fraction of 18,9%. During the follow-up to 6 first
months there were no cases of death or heart transplantation. They were defined as
responders the 47,8% from the patients, while the 52,2% remaining was classified as
non-responders. The percentage of patients who did not require hospitalizations after the
therapy was from 51,1%, and the 65,2% improved functional class and 68,5% ejection fraction.

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